Vitamin K for Injection (Phytonadione Injectable Emulsion) I0 mg Per mL Single-dose Vials 1 mL x 10/Tray

Vitamin K for Injection (Phytonadione Injectable Emulsion) 10 mg is used to treat and prevent bleeding due to vitamin K deficiency. It is commonly administered to reverse the effects of anticoagulant medications, such as warfarin, in cases of overdose or before surgery. This injectable form is crucial in managing bleeding disorders and is also given to newborn infants to prevent bleeding. Vitamin K promotes blood clotting, ensuring normal coagulation processes in the body, and is essential for individuals with impaired absorption.

Introducing Vitamin K for Injection (Phytonadione Injectable Emulsion), a premier pharmaceutical formulation from Cipla USA, designed to meet the critical needs of healthcare professionals in the management of coagulation disorders. With a potency of 10 mg per mL, this injectable solution comes in a convenient single-dose vial, meticulously packaged in a tray of ten 1 mL vials. This product exemplifies Cipla’s commitment to quality, efficacy, and safety, ensuring optimal patient outcomes in diverse clinical settings.

Product Details and Features:

Concentration and Packaging: Each single-dose vial contains 10 mg/mL of Phytonadione, the bioactive form of Vitamin K, enabling precise dosing tailored to patient-specific needs. Vials are presented in trays of 10, ensuring ease of access and inventory management.
Manufacturer: Cipla USA, a trusted name in the pharmaceutical industry, known for its rigorous quality standards and innovative healthcare solutions.
Stability and Shelf-life: Formulated for stability, the product ensures maintained potency throughout its shelf-life under recommended storage conditions.
Injectable Emulsion: Designed for rapid and effective absorption through intravenous or intramuscular routes, facilitating quick therapeutic action.

Mechanism of Action:

Vitamin K plays an essential role in the synthesis of blood clotting factors II, VII, IX, and X in the liver, along with the anticoagulant proteins C and S. Phytonadione, as the synthetic form of Vitamin K, supplants deficiencies and restores normal clotting activity. Upon administration, it facilitates the carboxylation of specific glutamic acid residues on the precursors of these clotting factors, ultimately enhancing coagulation to prevent or manage bleeding episodes.

Directions:

Administration: Administer Vitamin K for Injection through intravenous or intramuscular routes as per physician directives.
Dosage: The dosage should be individualized based on patient condition, coagulation test results, and clinical response. Refer to physician guidelines for precise dosing protocols.

Warnings:

• Allergic Reactions: Potential for hypersensitivity reactions including anaphylactoid reactions. Administer with caution in patients with a history of allergies.
• Intravenous Infusion Rate: Rapid intravenous administration may induce reactions. Ensure slow infusion to mitigate such risks.
• Use in Pregnant or Nursing Women: Administer only if clearly needed, as safety in these populations has not been fully established.
• Drug Interactions: Be aware of potential interactions with anticoagulants like warfarin. Monitor prothrombin time and adjust doses of interacting drugs as necessary.

Side Effects:

• Common Effects: Injection site reactions such as erythema, pain, or swelling; dizziness, or altered taste.
  
• Serious Effects: Anaphylactoid reactions, respiratory distress, or cutaneous flushing can occur; seek immediate medical attention if these develop.
  
• Other Reactions: Document and report any unexpected adverse effects for further evaluation.

Cipla USA’s Vitamin K for Injection positions itself as an indispensable ally in the armamentarium of healthcare professionals, providing a crucial intervention for bleeding disorders with safe and reliable results.