EDA Polyclonal Antibody Store at -20°C
SKU # | E-AB-11176 |
Reactivity | Human, Mouse |
Host | Rabbit |
Applications | IHC |
Product Details
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human EDA |
Abbre | EDA |
Synonyms | ECTD1, ECTODYSPLASIN, ECTODYSPLASIN A1 ISOFORM, ECTODYSPLASIN A2 ISOFORM, Ectodermal dysplasia, Ectodermal dysplasia 1, Ectodermal dysplasia protein, Ectodysplasin A, anhidrotic, anhidrotic (hypohydrotic), membrane form, secreted form |
Swissprot |
Q92838
|
Cellular Localization | Secreted and Cell membrane. |
Concentration | 0.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Developmental Biology, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
Applications | Recommended Dilution |
IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
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